Significant bone loss after stopping long-term denosumab treatment: a post FREEDOM study

Author:

Zanchetta M. B.ORCID,Boailchuk J.,Massari F.,Silveira F.,Bogado C.,Zanchetta J. R.

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism

Reference20 articles.

1. Cummings SR, San Martin J, McClung MR, Siris ES, Eastell R, Reid IR, Delmas P, ZoogHB AM, Wang A, Kutilek S, Adami S, Zanchetta J, Libanati C, Siddhanti S, Christiansen C, Trial F (2009) Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 361:756–765

2. Langdahl BL, Teglbjærg CS, Ho PR, Chapurlat R, Czerwinski E, Kendler DL, Reginster JY et al (2015) A 24-month study evaluating the efficacy and safety of denosumab for the treatment of men with low bone mineral density: results from the ADAMO trial. J Clin Endocrinol Metab 100(4):1335–1342. https://doi.org/10.1210/jc.2014-4079

3. Fizazi K, Carducci M, Smith M, Damião R, Brown J, Karsh L et al (2011) Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study. Lancet 377(9768):813–822. https://doi.org/10.1016/S0140-6736(10)62344-6

4. Stopeck A., Martin M., Ritchie D., Body J.J., Paterson A., Viniegra M., et al. (2010) Effect of denosumab versus zoledronic acid treatment in patients with breast cancer and bone metastases: results from the extended blinded treatment phase. Cancer Res 2010: P6-14-01–P6-14-01. https://doi.org/10.1016/j.ejca.2015.09.011

5. Freemantle N, Satram-Hoang S, Tang ET, Kaur P, Macarios D, Siddhanti S, Borenstein J et al (2012 Jan) Final results of the DAPS (Denosumab Adherence Preference Satisfaction) study: a 24-month, randomized, crossover comparison with alendronate in postmenopausal women. Osteoporos Int 23(1):317–326. https://doi.org/10.1007/s00198-011-1780-1

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