TPC Functions in the Immune System

Author:

Steiner Philip,Arlt Elisabeth,Boekhoff Ingrid,Gudermann Thomas,Zierler Susanna

Publisher

Springer International Publishing

Reference117 articles.

1. Arlt E, Fraticelli M, Tsvilovskyy V, Nadolni W, Breit A, O’Neill TJ, Resenberger S, Wennemuth G, Wahl-Schott C, Biel M, Grimm C, Freichel M, Gudermann T, Klugbauer N, Boekhoff I, Zierler S (2020) TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity. Proc Natl Acad Sci U S A 117(30):18068–18078. https://doi.org/10.1073/pnas.1920122117

2. Atakpa P, van Marrewijk LM, Apta-Smith M, Chakraborty S, Taylor CW (2019) GPN does not release lysosomal Ca2+ but evokes Ca2+ release from the ER by increasing the cytosolic pH independently of cathepsin C. J Cell Sci 132(3). https://doi.org/10.1242/jcs.223883

3. Beeton C, Wulff H, Barbaria J, Clot-Faybesse O, Pennington M, Bernard D, Cahalan MD, Chandy KG, Beraud E (2001) Selective blockade of T lymphocyte K+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis. Proc Natl Acad Sci U S A 98(24):13942–13947. https://doi.org/10.1073/pnas.241497298

4. Berg TO, Stromhaug E, Lovdal T, Seglen O, Berg T (1994) Use of glycyl-L-phenylalanine 2-naphthylamide, a lysosome-disrupting cathepsin C substrate, to distinguish between lysosomes and prelysosomal endocytic vacuoles. Biochem J 300(Pt 1):229–236. https://doi.org/10.1042/bj3000229

5. Boccaccio A, Scholz-Starke J, Hamamoto S, Larisch N, Festa M, Gutla PV, Costa A, Dietrich P, Uozumi N, Carpaneto A (2014) The phosphoinositide PI(3,5)P2 mediates activation of mammalian but not plant TPC proteins: functional expression of endolysosomal channels in yeast and plant cells. Cell Mol Life Sci 71(21):4275–4283. https://doi.org/10.1007/s00018-014-1623-2

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