The effects of tolvaptan on patients with severe chronic kidney disease complicated by congestive heart failure

Author:

Otsuka Tomoyuki,Sakai Yukinao,Ohno Dai,Murasawa Tsuneo,Sato Naoki,Tsuruoka Shuichi

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Nephrology,Physiology

Reference14 articles.

1. Yamamura Y, Nakamura S, Itoh S, et al. OPC-41061, a highly potent human vasopressin V2-receptor antagonist: pharmacological profile and aquaretic effect by single and multiple oral dosing in rats. J Pharmacol Exp Ther. 1998;287:860–7. http://www.ncbi.nlm.nih.gov/pubmed/9864265 .

2. Hirano T, Yamamura Y, Nakamura S, Onogawa T, Mori T. Effects of the V(2)-receptor antagonist OPC-41061 and the loop diuretic furosemide alone and in combination in rats. J Pharmacol Exp Ther. 2000;292:288–94. http://www.ncbi.nlm.nih.gov/pubmed/10604960 .

3. Gheorghiade M, Niazi I, Ouyang J, et al. Vasopressin V2-receptor blockade with tolvaptan in patients with chronic heart failure: results from a double-blind, randomized trial. Circulation. 2003;107:2690–6. http://www.ncbi.nlm.nih.gov/pubmed/12742979 .

4. Gheorghiade M, Gattis WA, O’Connor CM, et al. Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure. JAMA. 2004;291:1963–71.

5. Gheorghiade M, Orlandi C, Burnett JC, et al. Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to Evaluate the Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan (EVEREST). J Card Fail. 2005;11:260–9.

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