Optimal conditions and the advantages of using laser microdissection and liquid chromatography tandem mass spectrometry for diagnosing renal amyloidosis

Author:

Aoki Michiko,Kang Dedong,Katayama Akira,Kuwahara Naomi,Nagasaka Shinya,Endo Yoko,Terasaki Mika,Kunugi Shinobu,Terasaki Yasuhiro,Shimizu Akira

Funder

Grants-in-Aid for Scientific Research from the Japan Society for the Promotion of Science C

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Nephrology,Physiology

Reference26 articles.

1. Merlini G, Bellotti V. Molecular mechanisms of amyloidosis. N Engl J Med. 2003;349(6):583–96.

2. Satoskar AA, Burdge K, Cowden DJ, Nadasdy GM, Hebert LA, Nadasdy T. Typing of amyloidosis in renal biopsies: diagnostic pitfalls. Arch Pathol Lab Med. 2007;131(6):917–22.

3. Picken MM. Immunoglobulin light and heavy chain amyloidosis AL/AH: renal pathology and differential diagnosis. Contrib Nephrol. 2007;153:135–55.

4. Picken MM, Jerrera GA. The burden of “sticky” amyloid:typing challenges. Arch Pathol Lab Med. 2007;131(6):850–51.

5. Sethi S, Theis JD, Leung N, Dispenzieri A, Nasr SH, Fidler ME, et al. Mass spectrometry-based proteomic diagnosis of renal immunoglobulin heavy chain amyloidosis. Clin J Am Soc Nephrol. 2010;5(12):2180–7.

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