Abstract
Abstract
Background
Malaria epidemics are increasing in East Africa since the 1980s, coincident with rising temperature and widening climate variability. A projected 1–3.5 °C rise in average global temperatures by 2100 could exacerbate the epidemics by modifying disease transmission thresholds. Future malaria scenarios for the Lake Victoria Basin (LVB) are quantified for projected climate scenarios spanning 2006–2100.
Methods
Regression relationships are established between historical (1995–2010) clinical malaria and anaemia cases and rainfall and temperature for four East African malaria hotspots. The vector autoregressive moving average processes model, VARMAX (p,q,s), is then used to forecast malaria and anaemia responses to rainfall and temperatures projected with an ensemble of eight General Circulation Models (GCMs) for climate change scenarios defined by three Representative Concentration Pathways (RCPs 2.6, 4.5 and 8.5).
Results
Maximum temperatures in the long rainy (March–May) and dry (June–September) seasons will likely increase by over 2.0 °C by 2070, relative to 1971–2000, under RCPs 4.5 and 8.5. Minimum temperatures (June–September) will likely increase by over 1.5–3.0 °C under RCPs 2.6, 4.5 and 8.5. The short rains (OND) will likely increase more than the long rains (MAM) by the 2050s and 2070s under RCPs 4.5 and 8.5. Historical malaria cases are positively and linearly related to the 3–6-month running means of monthly rainfall and maximum temperature. Marked variation characterizes the patterns projected for each of the three scenarios across the eight General Circulation Models, reaffirming the importance of using an ensemble of models for projections.
Conclusions
The short rains (OND), wet season (MAM) temperatures and clinical malaria cases will likely increase in the Lake Victoria Basin. Climate change adaptation and mitigation strategies, including malaria control interventions could reduce the projected epidemics and cases. Interventions should reduce emerging risks, human vulnerability and environmental suitability for malaria transmission.
Funder
Deutsche Forschungsgemeinschaft
Horizon 2020 Framework Programme
Universität Hohenheim
Publisher
Springer Science and Business Media LLC
Reference62 articles.
1. World Health Organisation (2019) World Malaria Report. World Health Organization, Geneva. https://www.who.int/publications/i/item/9789241565721 (ISBN: 978-92-4-156572-1)
2. Hay SI, Rogers DJ, Randolph SE, Stern DI, Cox J, Shanks GD et al (2002) Hot topic or hot air? Climate change and malaria resurgence in East African highlands. Trends Parasitol 18(12):530–534. https://doi.org/10.1016/S1471-4922(02)02374-7
3. Himeidan YE, Kweka EJ (2012) Malaria in East African highlands during the past 30 years: impact of environmental changes. Front Physiol 3:315. https://doi.org/10.3389/fphys.2012.00315
4. World Health Organisation (2013) Methods for achieving universal coverage with long-lasting insecticidal nets in malaria control. Geneva
5. Githeko AK, Ogallo L, Lemnge M, Okia M, Ototo EN (2014) Development and validation of climate and ecosystem-based early malaria epidemic prediction models in East Africa. Malar J 13(1):329
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