Glutathione S-Transferase Gene Associations and Gene-Environment Interactions for Asthma

Author:

Dai Xin,Bui Dinh S,Lodge Caroline

Publisher

Springer Science and Business Media LLC

Subject

Pulmonary and Respiratory Medicine,Immunology and Allergy,Immunology

Reference51 articles.

1. Milos J, Maria Z, Eva B. Oxidative stress and bronchial asthma in children—causes or consequences? Front Pediatr. 2017;5:Article 162. https://doi.org/10.3389/fped.2017.00162.

2. •• Piacentini S, Polimanti R, Simonelli I, Donno S, Pasqualetti P, Manfellotto D, et al. Glutathione S-transferase polymorphisms, asthma susceptibility and confounding variables: a meta-analysis. Mol Biol Rep. 2013;40(4):3299–314 A comprehensive review and meta-analysis reporting the estimated effects of GST genes on asthma, giving evidence for gene-environment interaction.

3. Holley SL, Fryer AA, Haycock JW, Grubb SEW, Strange RC, Hoban PR. Differential effects of glutathione S-transferase pi (GSTP1) haplotypes on cell proliferation and apoptosis. Carcinogenesis. 2007;28(11):2268–73. https://doi.org/10.1093/carcin/bgm135.

4. • Fryer AA, Bianco A, Hepple M, Jones PW, Strange RC, Spiteri MA. Polymorphism at the glutathione S-transferase GSTP1 locus. A new marker for bronchial hyperresponsiveness and asthma. Am J Respir Crit Care Med. 2000;161(5):1437–42 This study provides clear information on GSTP1 and evidence on GSTP1 risk alleles.

5. •• Dai X, Bowatte G, Lowe AJ, Matheson MC, Gurrin LC, Burgess JA, et al. Do glutathione S-transferase genes modify the link between indoor air pollution and asthma, allergies, and lung function? A systematic review. Curr Allergy Asthma Rep. 2018;18. https://doi.org/10.1007/s11882-018-0771-0This systematic review synthesized evidence for interactions of GST genes with household air pollution, on asthma and lung function.

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