The role of neuroeffector mechanisms in the pathogenesis of asthma
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pulmonary and Respiratory Medicine,Immunology and Allergy,Immunology
Link
http://link.springer.com/content/pdf/10.1007/s11882-001-0081-8.pdf
Reference78 articles.
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2. Klapproth H, Reinheimer T, Metzen J, et al.: Non-neuronal acetylcholine, a signalling molecule synthesised by surface cells of rat and man. Naunyn Schmiedebergs Arch Pharmacol 1997, 355:515–523.
3. Wessler I, Kirkpatrick CJ, Racke K: Non-neuronal acetylcholine, a locally acting molecule, widely distributed in biological systems: expression and function in humans. Pharmacol Ther 1998, 77:59–79. This is an extensive review of the experiments demonstrating that the cholinergic system is widely distributed in nonneuronal cells in humans. The synthesizing enzyme choline acetyltransferase, the signaling molecule acetylcholine, and the respective receptors (nicotinic or muscarinic) are expressed in epithelial cells, including those of the human airways.
4. Reinheimer T, Baumgartner D, Hohle KD, et al.: Acetylcholine via muscarinic receptors inhibits histamine release from human isolated bronchi. Am J Respir Crit Care Med 1997, 156:389–395.
5. D’Agostino G, Erbelding D, Kilbinger H: Tachykinin NK(2) receptors facilitate acetylcholine release from guinea-pig isolated trachea. Eur J Pharmacol 2000, 396:29–32.
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