Use of Humanized Rat Basophilic Leukemia Reporter Cell Lines as a Diagnostic Tool for Detection of Allergen-Specific IgE in Allergic Patients: Time for a Reappraisal?-Reference-Cited by-同舟云学术

Use of Humanized Rat Basophilic Leukemia Reporter Cell Lines as a Diagnostic Tool for Detection of Allergen-Specific IgE in Allergic Patients: Time for a Reappraisal?

Published:2015-10-09 Issue:11 Volume:15 Page:
ISSN:1529-7322
Container-title:Current Allergy and Asthma Reports
language:en
Short-container-title:Curr Allergy Asthma Rep

Author:

Falcone Franco H.,Alcocer Marcos J. C.,Okamoto-Uchida Yoshimi,Nakamura Ryosuke

Publisher

Springer Science and Business Media LLC

Subject

Pulmonary and Respiratory Medicine,Immunology and Allergy,Immunology

Link

http://link.springer.com/content/pdf/10.1007/s11882-015-0568-3.pdf

Reference54 articles.

1. Falcone FH, Haas H, Gibbs BF. The human basophil: a new appreciation of its role in immune responses. Blood. 2000;96:4028–38.

2. Fleischer DM, Burks AW. Pitfalls in food allergy diagnosis: serum IgE testing. J Pediatr. 2015;166:8–10. Up-to-date editorial summarising the key problems regarding the difficulties of diagnosing food allergy, in particular due to the gap between sensitization (the occurrence of sIgE in patient blood) and the presence or absence of clinical symptoms.

3. Cox L, Williams B, Sicherer S, Oppenheimer J, Sher L, Hamilton R, et al. Pearls and pitfalls of allergy diagnostic testing: report from the American College of Allergy, Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specific IgE Test Task Force. Ann Allergy Asthma Immunol. 2008;101:580–92.

4. Blackley CH. Experimental researches on the causes and nature of catarrhus æstivus (hay-fever or hay-asthma). 1873. Available from: doi: 10.1097/00000441-187413300-00026

5. Santos AF, James LK, Bahnson HT, Shamji MH, Couto-Francisco NC, Islam S, et al. IgG4 inhibits peanut-induced basophil and mast cell activation in peanut-tolerant children sensitized to peanut major allergens. J Allergy Clin Immunol. 2015;135:1249–56. This work clearly demonstrates the benefits of using in vitro cellular readouts when studying sensitization patterns. Levels of allergen-specific IgE were only in part able to explain the observed differences in clinical reactivity between allergic and sensitized, but tolerant patients. Depletion experiments successfully demonstrated the importance of IgG4 in plasma samples of peanut-sensitized tolerant patients as a blocking antibody.

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel IgE crosslinking-induced luciferase expression method using human-rat chimeric IgE receptor-carrying mast cells;Journal of Immunological Methods;2024-06

2. Specific IgE and Basophil Activation Test by Microarray: A Promising Tool for Diagnosis of Platinum Compound Hypersensitivity Reactions;International Journal of Molecular Sciences;2024-03-31

3. Rapid generation of an RBL cellular model to study proteins that cause allergenic reactions in vitro;Immunologic Research;2024-02-09

4. Allergenic Activity of Individual Cat Allergen Molecules;International Journal of Molecular Sciences;2023-11-24

5. Biological activity of human IgE monoclonal antibodies targeting Der p 2, Fel d 1, Ara h 2 in basophil mediator release assays;Frontiers in Immunology;2023-05-09