Skin cancer induction by UV radiation: molecular UV targets and quantitative risk models

Author:

de Gruijl Frank R.,Slaper Harry

Publisher

Springer Netherlands

Reference49 articles.

1. Brash DE, Rudolph JA, Simon JA, et al. (1991) A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinomas. Proc Natl Acad Sci USA 88: 10124–10128.

2. Ziegler AD, Leffel DJ, Kunala S, et al. (1993) Mutation hotspots due to sunlight in the p53 gene of skin cancers. Proc Natl Acad Sci USA 90: 4216–4220.

3. Kress S, Sutter SC, Strickland PT, Mukhtar H, Schweizer J, Schwarz M (1992) Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin. Cancer Res 52: 6400–6403.

4. Kanjilal S, Pierceall WF, Cummings KK, Kripke ML, Ananthaswamy HN (1993) High frequency of p53 mutations in ultraviolet radiation-induced skin tumors: evidence for strand bias and tumor heterogeneity. Cancer Res 53: 2961–2964.

5. Van Kranen HJ, de Gruijl FR, de Vries A, et al. (1995) Frequent p53 alterations but low incidences of ras mutations in UV-B induced skin tumors of hairless mice. Carcinogenesis 16: 1141–1147.

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