Integration of New and Classical Techniques in Drug Development. PET Application to Propionyl-L-Carnitine Pharmacokinetic Study

Author:

Longo A.,Fiore F.,Law M. P.,Mancinelli A.,Pike V.,Camici P. G.

Publisher

Springer Netherlands

Reference5 articles.

1. F.Di Lisa, R.Barbato, R.Menabò and N.Siliprandi “Carnitine and Carnitine esters in mitochondrial metabolism and function” (1994; in press).

2. A.Mancinelli, A.Longo, K.Shanahan and A.M.Evans “Disposition of L-carnitine and Acetyl-L-carnitine in the isolated perfused rat kidney” (Journal of Pharmacology and Experimental terapheutics, 1995; in press).

3. R.J.Davemport, M.P.Law, W.Pike, S.Osman and K.G.P.Poole “Propionyl-L-carnitine - labelling in the N-methyl position with carbon-11 and pharmacokinetics studies in rats” (1994; in press).

4. S.D.Rosen, V.Cunninghan, H.Boyd, V.Pike, R.J.Davemport, R.Gunn, S.Osman, M.P.Law and P.G.Camici “Myocardial uptake of [N-methyl- 11 C] Propionyl-L-carnitine in man” (1994; in press).

5. A.Peschechera, E.L.Ferrari, E.Arrigoni Martelli and W.C.Hulsmann “Uptake and release of Carnitine by vascular endothelium in cultures; effects of protons and oxygen free radicals” (Molecular and Cellular Biochemistry; 1994; in press).

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