Predictive value of PCT and IL-6 for bacterial infection in children with cancer and febrile neutropenia

Author:

van der Galiën Hilde T.,Loeffen Erik A. H.,Miedema Karin G. E.,Tissing Wim J. E.

Funder

University Medical Center Groningen

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference30 articles.

1. Lehrnbecher T, Robinson P, Fisher B, Alexander S, Ammann RA, Beauchemin M, Carlesse F, Groll AH, Haeusler GM, Santolaya M, Steinbach WJ, Castagnola E, Davis BL, Dupuis LL, Gaur AH, Tissing WJE, Zaoutis T, Phillips R, Sung L (2017) Guideline for the management of fever and neutropenia in children with cancer and hematopoietic stem-cell transplantation recipients: 2017 update. J Clin Oncol 35:2082–2094. https://doi.org/10.1200/JCO.2016.71.7017

2. Stryjewski GR, Nylen ES, Bell MJ, Snider RH, Becker KL, Wu A, Lawlor C, Dalton H (2005) Interleukin-6, interleukin-8, and a rapid and sensitive assay for calcitonin precursors for the determination of bacterial sepsis in febrile neutropenic children. Pediatr Crit Care Med 6:129–135. https://doi.org/10.1097/01.PCC.0000149317.15274.48

3. Macher E, Dubos F, Garnier N, Delebarre M, de Berranger E, Thebaud E, Mazingue F, Leblond P, Martinot A (2010) Predicting the risk of severe bacterial infection in children with chemotherapy-induced febrile neutropenia. Pediatr Blood Cancer 55:662–667. https://doi.org/10.1002/pbc.22586

4. Miedema KGE, Tissing WJE, Abbink FCH, Ball LM, Michiels EMC, van Vliet MJ, de Vries WY, Kamps WA, Norbruis OF, Fiocco M, de Groot-Kruseman HA, van de Wetering MD, de Bont ESJM (2016) Risk-adapted approach for fever and neutropenia in paediatric cancer patients—a national multicentre study. Eur J Cancer 53:16–24. https://doi.org/10.1016/j.ejca.2015.10.065

5. Ammann RA, Hirt A, Lüthy AR, Aebi C (2003) Identification of children presenting with fever in chemotherapy-induced neutropenia at low risk for severe bacterial infection. Med Pediatr Oncol 41:436–443. https://doi.org/10.1002/mpo.10320

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