Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases

Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases—a pilot study

Published:2007-01-23 Issue:6 Volume:15 Page:643-647
ISSN:0941-4355
Container-title:Supportive Care in Cancer
language:en
Short-container-title:Support Care Cancer

Author:

Chow Edward,Loblaw Andrew,Harris Kristin,Doyle Meagan,Goh Philiz,Chiu Hannah,Panzarella Tony,Tsao May,Barnes Elizabeth A.,Sinclair Emily,Farhadian Macey,Danjoux Cyril

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Link

http://link.springer.com/content/pdf/10.1007/s00520-007-0217-z.pdf

Reference5 articles.

1. Wu J, Wong R, Johnston M et al (2003) Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases. Int J Radiation Oncology Biol Phys 55(3):594–605

2. Loblaw DA, Wu JSY, Warde P et al (2001) Pain flare after palliative radiotherapy for osseous metastases: a nested randomized controlled trial of single versus multiple fractions. Proc Amer Soc Clin Oncol 20(1):395a, (abstract 1578)

3. Kirkbride PA, Bezjak A, Pater J et al (2000) Dexamethasone for the prophylaxis for radiation-induced emesis: a National Cancer Institute of Canada Clinical Trails Group Phase III Study. J Clin Oncol 18(9):1960–1966

4. Fleming TR (1982) One-sample multiple testing procedure for Phase II clinical trials. Biometrics 38:143–151

5. Chow E, Ling A, Davis L et al (2005) Pain flare following external beam radiotherapy and meaningful change in pain scores in the treatment of bone metastases. Radiother Oncol 75:64–69

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