Irinotecan-induced neutropenia is reduced by oral alkalization drugs: analysis using retrospective chart reviews and the spontaneous reporting database

Author:

Hamano Hirofumi,Mitsui Marin,Zamami Yoshito,Takechi Kenshi,Nimura Takahiro,Okada Naoto,Fukushima Keijo,Imanishi Masaki,Chuma Masayuki,Horinouchi Yuya,Izawa-Ishizawa Yuki,Kirino Yasushi,Nakamura Toshimi,Teraoka Kazuhiko,Ikeda Yasumasa,Fujino Hiromichi,Yanagawa Hiroaki,Tamaki Toshiaki,Ishizawa Keisuke

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference26 articles.

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2. Takeuchi S, Dobashi K, Fujimoto S, Tanaka K, Suzuki M, Terashima Y, Hasumi K, Akiya K, Negishi Y, Tamaya T et al (1991) A late phase II study of CPT-11 on uterine cervical cancer and ovarian cancer. Research groups of CPT-11 in gynecologic cancers. Gan To Kagaku Ryoho 18(10):1681–1689

3. Matsumoto K, Katsumata N, Yamanaka Y, Yonemori K, Kohno T, Shimizu C, Andoh M, Fujiwara Y (2006) The safety and efficacy of the weekly dosing of irinotecan for platinum- and taxanes-resistant epithelial ovarian cancer. Gynecol Oncol 100(2):412–416. https://doi.org/10.1016/j.ygyno.2005.10.013

4. Fukuoka M, Niitani H, Suzuki A, Motomiya M, Hasegawa K, Nishiwaki Y, Kuriyama T, Ariyoshi Y, Negoro S, Masuda N et al (1992) A phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer. J Clin Oncol Off J Am Soc Clin Oncol 10(1):16–20. https://doi.org/10.1200/jco.1992.10.1.16

5. Takasuna K, Hagiwara T, Hirohashi M, Kato M, Nomura M, Nagai E, Yokoi T, Kamataki T (1996) Involvement of beta-glucuronidase in intestinal microflora in the intestinal toxicity of the antitumor camptothecin derivative irinotecan hydrochloride (CPT-11) in rats. Cancer Res 56(16):3752–3757

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