Safety and tolerability of velafermin (CG53135-05) in patients receiving high-dose chemotherapy and autologous peripheral blood stem cell transplant

Author:

Schuster Michael W.,Shore Tsiporah B.,Harpel John G.,Greenberg June,Jalilizeinali Bita,Possley Scott,Gerwien Robert W.,Hahne William,Halvorsen Yuan-Di C.

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference20 articles.

1. Alvarez E, Fey EG, Valax P, Yim Z, Peterson JD, Mesri M et al (2003) Preclinical characterization of CG53135 (FGF-20) in radiation and concomitant chemotherapy/radiation-induced oral mucositis. Clin Cancer Res 9(9):3454–3461

2. Alvarez E, Gerlach VL, Gerwien RW, Fey EG, Watkins BA, Hahne WF et al (2005) Single-dose prevention or short-term treatment with fibroblast growth factor-20 (CG53135–05) reduces the severity and duration of oral mucositis. Support Cancer Ther 2(2):122–127

3. Chamorro MN, Schwartz DR, Vonica A, Brivanlou AH, Cho KR, Varmus HE (2005) FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development. EMBO J 24(1):73–84

4. Crawford J, Tomita DK, Mazanet R, Glaspy J, Ozer H (1999) Reduction of oral mucositis by filgrastim (r-metHuG-CSF) in patients receiving chemotherapy. Cytokines Cell Mol Ther 5(4):187–193

5. Dailey L, Ambrosetti D, Mansukhani A, Basilico C (2005) Mechanisms underlying differential responses to FGF signaling. Cytokine Growth Factor Rev 16(2):233–247

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