Systemic inflammation adversely affects response to anamorelin in patients with pancreatic cancer
Author:
Funder
Japan Society for the Promotion of Science
Princess Takamatsu Cancer Research Fund
Publisher
Springer Science and Business Media LLC
Subject
Oncology
Link
https://link.springer.com/content/pdf/10.1007/s00520-023-08206-3.pdf
Reference16 articles.
1. Temel JS, Abernethy AP, Currow DC, Friend J, Duus EM, Yan Y et al (2016) Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials. Lancet Oncol 17:519–531. https://doi.org/10.1016/S1470-2045(15)00558-6
2. Currow D, Temel JS, Abernethy A, Milanowski J, Friend J, Fearon KC (2017) ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia. Ann Oncol 28:1949–1956. https://doi.org/10.1093/annonc/mdx192
3. Katakami N, Uchino J, Yokoyama T, Naito T, Kondo M, Yamada K et al (2018) Anamorelin (ONO-7643) for the treatment of patients with non-small cell lung cancer and cachexia: results from a randomized, double-blind, placebo-controlled, multicenter study of Japanese patients (ONO-7643-04). Cancer 124:606–616. https://doi.org/10.1002/cncr.31128
4. Hamauchi S, Furuse J, Takano T, Munemoto Y, Furuya K, Baba H et al (2019) A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in advanced gastrointestinal cancer patients with cancer cachexia. Cancer 125:4294–4302. https://doi.org/10.1002/cncr.32406
5. Iwai N, Sakai H, Oka K, Sakagami J, Okuda T, Hattori C et al (2023) Predictors of response to anamorelin in gastrointestinal cancer patients with cachexia: a retrospective study. Support Care Cancer 31:115. https://doi.org/10.1007/s00520-023-07576-y
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