UFLC–MS/MS Determination and Population Pharmacokinetic Study of Tanshinol, Ginsenoside Rb1 and Rg1 in Rat Plasma After Oral Administration of Compound Danshen Dripping Pills-Reference-Cited by-同舟云学术

UFLC–MS/MS Determination and Population Pharmacokinetic Study of Tanshinol, Ginsenoside Rb1 and Rg1 in Rat Plasma After Oral Administration of Compound Danshen Dripping Pills

Published:2020-04-17 Issue:4 Volume:45 Page:523-533
ISSN:0378-7966
Container-title:European Journal of Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Eur J Drug Metab Pharmacokinet

Author:

Jin Tianqian,Liu Zuhui,Chu Yang,Ma Xiaohui,Li Shuming,Wang Xiangyang,Wang Genbei,Zhou Shuiping,Sun He,Yang Jin

Funder

Tianjin Science & Technology Plan Project

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Link

https://link.springer.com/content/pdf/10.1007/s13318-020-00618-4.pdf

Reference27 articles.

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2. Zhang L, Zheng J, Li H, Meng Y. Inhibitory effects of cardiotonic pills on platelet function in dogs fed a high-fat diet. Blood Coagul Fibrinolysis. 2006;17(4):259–64. https://doi.org/10.1097/01.mbc.0000224844.33216.91.

3. Guo J, Yong Y, Aa J, Cao B, Sun R, Yu X, et al. Compound danshen dripping pills modulate the perturbed energy metabolism in a rat model of acute myocardial ischemia. Sci Rep. 2016;6:37919. https://doi.org/10.1038/srep37919.

4. Zhao N, Liu Y, Wang F, Hu B, Sun K, Chang X, et al. Cardiotonic pills, a compound Chinese medicine, protects ischemia-reperfusion-induced microcirculatory disturbance and myocardial damage in rats. Am J Physiol Heart Circ Physiol. 2010;298(4):H1166–H1176176. https://doi.org/10.1152/ajpheart.01186.2009.

5. Lam FF, Yeung JH, Chan KM, Or PM. Relaxant effects of danshen aqueous extract and its constituent Danshensu on rat coronary artery are mediated by inhibition of calcium channels. Vascul Pharmacol. 2007;46(4):271–7. https://doi.org/10.1016/j.vph.2006.10.011.

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