Abstract
AbstractThe three-dimensional stria vascularis (SV) and cochlear blood vessel structure is essential for inner ear function. Here, modified Sca/eS, a sorbitol-based optical-clearing method, was reported to visualize SV and vascular structure in the intact mouse cochlea. Cochlear macrophages as well as perivascular-resident macrophage-like melanocytes were detected as GFP-positive cells of the CX3CR1+/GFP mice. This study’s method was effective in elucidating inner ear function under both physiological and pathological conditions.
Funder
Japan Society for the Promotion of Science
The University of Tokyo
Publisher
Springer Science and Business Media LLC
Cited by
1 articles.
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