On the Effects of Leukemogenic Nucleoporin Fusion Proteins on Nucleocytoplasmic Transport and Gene Expression

Author:

Martins Nuno,Mendes Adélia,Fahrenkrog Birthe

Publisher

Springer International Publishing

Reference196 articles.

1. Abe A, Yamamoto Y, Iba S, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Kanie T, Tsuzuki M, Akatsuka Y, Mizuta S, Okamoto M, Kameyama T, Mayeda A, Emi N (2015) NUP214-RAC1 and RAC1-COL12A1 fusion in complex variant translocations involving chromosomes 6, 7 and 9 in an acute myeloid leukemia case with DEK-NUP214. Cytogenet Genome Res 146(4):279–284. https://doi.org/10.1159/000441464

2. Ageberg M, Drott K, Olofsson T, Gullberg U, Lindmark A (2008) Identification of a novel and myeloid specific role of the leukemia-associated fusion protein DEK-NUP214 leading to increased protein synthesis. Genes Chromosom Cancer 47(4):276–287. https://doi.org/10.1002/gcc.20531

3. Ahuja HG, Felix CA, Aplan PD (1999) The t(11;20)(p15;q11) chromosomal translocation associated with therapy-related myelodysplastic syndrome results in an NUP98-TOP1 fusion. Blood 94(9):3258–3261

4. Ahuja HG, Hong J, Aplan PD, Tcheurekdjian L, Forman SJ, Slovak ML (2000) t(9;11)(p22;p15) in acute myeloid leukemia results in a fusion between NUP98 and the gene encoding transcriptional coactivators p52 and p75-lens epithelium-derived growth factor (LEDGF). Cancer Res 60(22):6227–6229

5. Akiki S, Dyer SA, Grimwade D, Ivey A, Abou-Zeid N, Borrow J, Jeffries S, Caddick J, Newell H, Begum S, Tawana K, Mason J, Velangi M, Griffiths M (2013) NUP98-NSD1 fusion in association with FLT3-ITD mutation identifies a prognostically relevant subgroup of pediatric acute myeloid leukemia patients suitable for monitoring by real time quantitative PCR. Genes Chromosom Cancer 52(11):1053–1064. https://doi.org/10.1002/gcc.22100

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