Simulated Clinical Trials: Principle, Good Practices, and Focus on Virtual Patients Generation

Author:

Savy Nicolas,Savy Stéphanie,Andrieu Sandrine,Marque Sébastien

Publisher

Springer International Publishing

Reference11 articles.

1. Anisimov, V.V., Fedorov, V.V.: Modelling, prediction and adaptive adjustment of recruitment in multicentre trials. Stat. Med. 26(27), 4958–4975 (2007). https://doi.org/10.1002/sim.2956

2. Bonate, P., Gillespie, W., Ludden, T., Rubin, D., Stanski, D.: Simulation in drug development: Good practices. In: Holford, N., Hale, M., Ko, H., Steimer, J.L., Sheiner, L., Peck, C. (eds.) Published on the CDDS web site. http://holford.fmhs.auckland.ac.nz/docs/simulation-in-drug-development-good-practices.pdf (1999). Accessed 25 April 2017

3. Bonate, P.L.: Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Springer, New York (2011)

4. Brindley, P.G., Dunn, W.F.: Simulation for clinical research trials: a theoretical outline. J. Crit. Care 24(2), 164–167 (2009)

5. Holford, N., Ma, S.C., Ploeger, B.A.: Clinical trial simulation: a review. Clin. Pharmacol. Ther. 88(2), 166–182 (2010)

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