The Importance of β-Lactamases to the Development of New β-Lactams

Author:

Bush Karen

Publisher

Springer International Publishing

Reference126 articles.

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2. Selwyn S. The discovery and evolution of the penicillins and cephalosporins. In: The Beta-Lactam Antibiotics: penicillins and cephalosporins in perspective. London: Hodder and Stoughton; 1980. pp. 1–45.

3. Spratt BG. Penicillin-binding proteins and the future of β-lactam antibiotics. J Gen Microbiol. 1983;129:1247–60.

4. Tipper DJ, Strominger JL. Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine. Proc Natl Acad Sci U S A. 1965;54:1133–41.

5. Li X-Z, Ma D, Livermore DM, Nikaido H. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to β-lactam resistance. Antimicrob Agents Chemother. 1994;38:1742–52.

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