The EpiSkin™ Human Epidermis Model for In Vitro Skin Corrosion of Test Chemicals

Author:

Alépée Nathalie,Grandidier Marie Hélène,Cotovio José

Publisher

Springer International Publishing

Reference28 articles.

1. EC. Regulation (EC) no 1223/2009 of the European Parliament and of the council of 30 November 2009 on cosmetic products. Off J Eur Union. 2009;L342:59–209. Available at: http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32009R1223

2. EC. Regulation (EC) no 1907/2006 of the European Parliament and of the council of 18 December 2006 concerning the registration, evaluation, authorisation and restriction of chemicals (REACH), establishing a European Chemicals Agency, amending directive 1999/45/EC and repealing council regulation (EEC) No. 793/93 and commission regulation (EC) No. 1488/94 as well as council directive 76/769/EEC and commission directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Off J Eur Union. 2006;L396:1–1355.

3. Draize JH, Woodard G, Clavery HO. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Pharmacol Exp Ther. 1944;82:377–90.

4. Tinois E, Gaetani Q, Gavraud B, Dupond D, Rougier A, Pouradier-Dupteil X. The EPISKIN model: successful reconstruction of human epidermis in vitro. In: Rougier A, Goldberg M, Maibach HI, editors. In vitro skin toxicology. New York: Mary Ann Liebert; 1994. p. 133–40.

5. Alépée N, Grandidier MH, Cotovio J. Sub-categorisation of skin corrosive chemicals by the EpiSkin™ reconstructed human epidermis skin corrosion test method according to UN GHS: revision of OECD test guideline 431. Toxicol In Vitro. 2014;28:131–45.

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