Immunization Strategies Against Clostridium difficile

Author:

Bruxelle Jean-François,Péchiné Séverine,Collignon Anne

Publisher

Springer International Publishing

Reference148 articles.

1. Andersen KK, Strokappe NM, Hultberg A, Truusalu K, Smidt I, Mikelsaar R-H, Mikelsaar M, Verrips T, Hammarström L, Marcotte H (2015) Neutralization of Clostridium difficile toxin B mediated by engineered lactobacilli that produce single-domain antibodies. Infect Immun 84:395–406. https://doi.org/10.1128/IAI.00870-15

2. Anosova NG, Brown AM, Li L, Liu N, Cole LE, Zhang J, Mehta H, Kleanthous H (2013) Systemic antibody responses induced by a twocomponent Clostridium difficile toxoid vaccine protect against C. difficile-associated disease in hamsters. J Med Microbiol 62:1394–1404. https://doi.org/10.1099/jmm.0.056796-0

3. Anosova NG, Cole LE, Li L, Zhang J, Brown AM, Mundle S, Zhang J, Ray S, Ma F, Garrone P, Bertraminelli N, Kleanthous H, Anderson SF (2015) A combination of three fully human toxin A- and toxin B-specific monoclonal antibodies protects against challenge with highly virulent epidemic strains of Clostridium difficile in the hamster model. Clin Vaccine Immunol CVI 22:711–725. https://doi.org/10.1128/CVI.00763-14

4. Aronsson B, Granström M, Möllby R, Nord CE (1985) Serum antibody response to Clostridium difficile toxins in patients with Clostridium difficile diarrhoea. Infection 13:97–101

5. Baban ST, Kuehne SA, Barketi-Klai A, Cartman ST, Kelly ML, Hardie KR, Kansau I, Collignon A, Minton NP (2013) The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strain. PLoS One 8:e73026. https://doi.org/10.1371/journal.pone.0073026

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