IL-6 Receptor Blockade by Tocilizumab Has Anti-absence and Anti-epileptogenic Effects in the WAG/Rij Rat Model of Absence Epilepsy-Reference-Cited by-同舟云学术

IL-6 Receptor Blockade by Tocilizumab Has Anti-absence and Anti-epileptogenic Effects in the WAG/Rij Rat Model of Absence Epilepsy

Published:2020-07-17 Issue:4 Volume:17 Page:2004-2014
ISSN:1933-7213
Container-title:Neurotherapeutics
language:en
Short-container-title:Neurotherapeutics

Author:

Leo Antonio,Nesci Valentina,Tallarico Martina,Amodio Nicola,Gallo Cantafio Eugenia M.,De Sarro Giovambattista,Constanti Andrew,Russo Emilio^ORCID,Citraro Rita

Funder

Ministero della Salute

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Neurology (clinical),Pharmacology

Link

https://link.springer.com/content/pdf/10.1007/s13311-020-00893-8.pdf

Reference81 articles.

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3. Devinsky O, Vezzani A, Najjar S, et al. Glia and epilepsy: Excitability and inflammation. Trends Neurosci 2013; 36: 174–184.

4. Paudel YN, Shaikh MF, Shah S, et al. Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy. Eur J Pharmacol 2018; 837: 145–155.

5. Mazarati AM, Lewis ML, Pittman QJ. Neurobehavioral comorbidities of epilepsy: Role of inflammation. Epilepsia 2017; 58: 48–56.

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