Intranasal Dexamethasone Reduces Mortality and Brain Damage in a Mouse Experimental Ischemic Stroke Model

Author:

Espinosa Alejandro,Meneses Gabriela,Chavarría Anahí,Mancilla Raúl,Pedraza-Chaverri José,Fleury Agnes,Bárcena Brandon,Pérez-Osorio Ivan N.,Besedovsky Hugo,Arauz Antonio,Fragoso Gladis,Sciutto Edda

Funder

Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Neurology (clinical),Pharmacology

Reference50 articles.

1. Institute for Health Metrics and Evaluation (IHME). Findings from the Global Burden of Disease Study 2017. Seattle, WA: IHME, 2018.

2. López-Espuela F, Pedrera-Zamorano JD, Jiménez-Caballero PE, et al. Functional status and disability in patients after acute stroke: a longitudinal study. Am J Crit Care 2016;25:144−151.

3. Noe-Sebastian E, Balasch-Bernat M, Colomer-Font C, et al. Disability after stroke: a longitudinal study in moderate and severe stroke patients included in a multidisciplinary rehabilitation program. Rev Neurol 2017;64:385−392.

4. Gülke E, Gelderblom M, Magnus T. Danger signals in stroke and their role on microglia activation after ischemia. Ther Adv Neurol Disord 2018;11:1756286418774254.

5. Patel AR, Ritzel R, McCullough LD, Liu F. Microglia and ischemic stroke: a double-edged sword. Int J Physiol Pathophysiol Pharmacol 2013;5:73−90.

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