Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation-Reference-Cited by-同舟云学术

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Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation

Published:2021-02-02 Issue:2 Volume:18 Page:1137-1150
ISSN:1933-7213
Container-title:Neurotherapeutics
language:en
Short-container-title:Neurotherapeutics

Author:

Bamia Aline,Sinane Maha,Naït-Saïdi Rima,Dhiab Jamila,Keruzoré Marc,Nguyen Phu Hai,Bertho Agathe,Soubigou Flavie,Halliez Sophie,Blondel Marc,Trollet Capucine,Simonelig Martine,Friocourt Gaëlle,Béringue Vincent,Bihel Frédéric,Voisset Cécile^ORCID

Funder

Institut de France – Fondation NRJ

MESR

Inserm

UBO

CNRS

University of Montpellier

AFM-Téléthon eOPMD

Sorbonne Université

Association Institut de Myologie

DIM MALINF

INRAE

Fondation pour la Recherche Médicale

AFM-Téléthon

Association Défi Organisation

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Neurology (clinical),Pharmacology

Link

https://link.springer.com/content/pdf/10.1007/s13311-020-00992-6.pdf

Reference57 articles.

1. Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science 1982;216(4542):136-44. https://doi.org/10.1126/science.6801762.

2. Bach S, Talarek N, Andrieu T, et al. Isolation of drugs active against mammalian prions using a yeast-based screening assay. Nat Biotechnol 2003;21(9):1075-81.

3. Nguyen P, Oumata N, Soubigou F, et al. Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles. Eur J Med Chem 2014;82:363-71. https://doi.org/10.1016/j.ejmech.2014.05.083.

4. Nguyen PH, Hammoud H, Halliez S, et al. Structure-activity relationship study around guanabenz identifies two derivatives retaining antiprion activity but having lost alpha2-adrenergic receptor agonistic activity. ACS Chem Neurosci 2014;5(10):1075-82. https://doi.org/10.1021/cn5001588.

5. Oumata N, Nguyen PH, Beringue V, et al. The toll-like receptor agonist imiquimod is active against prions. PLoS One 2013;8(8):e72112. https://doi.org/10.1371/journal.pone.0072112.PONE-D-13-23175.

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