Anti-Inflammatory and Neuroprotective Effects of DIPOPA (N,N-Diisopropyl-2-Oxopropanamide), an Ethyl Pyruvate Bioisoster, in the Postischemic Brain-Reference-Cited by-同舟云学术

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Anti-Inflammatory and Neuroprotective Effects of DIPOPA (N,N-Diisopropyl-2-Oxopropanamide), an Ethyl Pyruvate Bioisoster, in the Postischemic Brain

Published:2019-01-24 Issue:2 Volume:16 Page:523-537
ISSN:1933-7213
Container-title:Neurotherapeutics
language:en
Short-container-title:Neurotherapeutics

Author:

Lee Hye-Kyung,Park Ju-Young,Lee Hahnbie,Kim Il-Doo,Kim Seung-Woo,Yoon Sung-Hwa,Lee Ja-Kyeong

Funder

Korea Health Industry Development Institute

National Research Foundation

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Clinical Neurology,Pharmacology

Link

http://link.springer.com/article/10.1007/s13311-019-00711-w/fulltext.html

Reference35 articles.

1. Venkataraman R, Kellum JA, Song M, Fink MP. Resuscitation with Ringer’s ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock. Shock 2002;18:507–512.

2. Ulloa L, Ochani M, Yang H, et al. Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proc Natl Acad Sci USA 2002; 99: 12351–12356.

3. Yang R, Uchiyama T, Alber SM, et al. Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis. Crit Care Med 2004; 32: 1453–1459.

4. Yu YM, Kim JB, Lee KW, Kim SY, Han PL, Lee JK. Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window. Stroke 2005; 36: 2238–2243.

5. Varma SD, Devamanoharan PS, Ali AH. Prevention of intracellular oxidative stress to lens by pyruvate and its ester. Free Radic Res 1998; 28: 131–135.

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