CREB Participates in Paclitaxel-Induced Neuropathic Pain Genesis Through Transcriptional Activation of Dnmt3a in Primary Sensory Neurons

Author:

Yang Yong,Wen Jing,Zheng Bixin,Wu Shaogen,Mao Qingxiang,Liang Lingli,Li Zhisong,Bachmann Thomas,Bekker Alex,Tao Yuan-XiangORCID

Funder

National Institute of Neurological Disorders and Stroke

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Neurology (clinical),Pharmacology

Reference44 articles.

1. Flatters SJL, Dougherty PM, Colvin LA (2017) Clinical and preclinical perspectives on Chemotherapy-Induced Peripheral Neuropathy (CIPN): a narrative review. Br J Anaesth 119: 737-749. S0007-0912(17)53816-7 [pii];https://doi.org/10.1093/bja/aex229 [doi].

2. Li Y, Tatsui CE, Rhines LD, North RY, Harrison DS, Cassidy RM, Johansson CA, Kosturakis AK, Edwards DD, Zhang H, Dougherty PM (2017) Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy. Pain 158: 417-429. https://doi.org/10.1097/j.pain.0000000000000774 [doi].

3. Li Y, North RY, Rhines LD, Tatsui CE, Rao G, Edwards DD, Cassidy RM, Harrison DS, Johansson CA, Zhang H, Dougherty PM (2018) DRG Voltage-Gated Sodium Channel 1.7 Is Upregulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain. J Neurosci 38: 1124-1136. JNEUROSCI.0899-17.2017 [pii];https://doi.org/10.1523/JNEUROSCI.0899-17.2017 [doi].

4. Sisignano M, Angioni C, Park CK, Meyer Dos SS, Jordan H, Kuzikov M, Liu D, Zinn S, Hohman SW, Schreiber Y, Zimmer B, Schmidt M, Lu R, Suo J, Zhang DD, Schafer SM, Hofmann M, Yekkirala AS, de BN, Parnham MJ, Woolf CJ, Ji RR, Scholich K, Geisslinger G (2016) Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain. Proc Natl Acad Sci U S A 113: 12544-12549. 1613246113 [pii];https://doi.org/10.1073/pnas.1613246113 [doi].

5. Zhang H, Dougherty PM (2014) Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy. Anesthesiology 120: 1463-1475. https://doi.org/10.1097/ALN.0000000000000176 [doi].

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