Brain Zinc Deficiency Exacerbates Cognitive Decline in the R6/1 Model of Huntington’s Disease
Author:
Funder
National Health and Medical Research Council
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Clinical Neurology,Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/s13311-019-00785-6.pdf
Reference28 articles.
1. MacDonald ME, Ambrose CM, Duyao MP, Myers RH, Lin C, Srinidhi L, et al. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes. Cell. 1993;72(6):971–983.
2. Pouladi MA, Morton AJ, Hayden MR. Choosing an animal model for the study of Huntington’s disease. Nature reviews Neuroscience. 2013;14(10):708–721.
3. Cherny RA, Ayton S, Finkelstein DI, Bush AI, McColl G, Massa SM. PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington’s Disease. J Huntingtons Dis. 2012;1(2):211–219.
4. Huntington Study Group Reach HDI. Safety, tolerability, and efficacy of PBT2 in Huntington’s disease: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet neurology. 2015;14(1):39–47.
5. Frederickson CJ. Neurobiology of zinc and zinc-containing neurons. International review of neurobiology. 1989;31:145–238.
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