Chemogenetic Seizure Control with Clozapine and the Novel Ligand JHU37160 Outperforms the Effects of Levetiracetam in the Intrahippocampal Kainic Acid Mouse Model
Author:
Funder
Fonds Wetenschappelijk Onderzoek
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Neurology (clinical),Pharmacology
Link
https://link.springer.com/content/pdf/10.1007/s13311-021-01160-0.pdf
Reference50 articles.
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2. Walker MC, Kullmann DM. Optogenetic and chemogenetic therapies for epilepsy. Neuropharmacology. Elsevier Ltd; 2020. p. 107751.
3. Forcelli PA. Applications of optogenetic and chemogenetic methods to seizure circuits: Where to go next? J Neurosci Res 2017;95:2345–2356.
4. Urban DJ, Roth BL. DREADDs (Designer Receptors Exclusively Activated by Designer Drugs): Chemogenetic Tools with Therapeutic Utility. Annu Rev Pharmacol Toxicol 2015;55:399–417.
5. Roth BL. DREADDs for Neuroscientists. Neuron 2016;89:683–694.
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