Endokavitäre Kontakttherapie vs. EBRT als Boost bei organerhaltender Strahlentherapie von T2–3-Rektumkarzinomen: Ergebnisse der OPERA-Studie
Author:
Funder
Universitätsklinikum Schleswig-Holstein - Campus Kiel
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Radiology, Nuclear Medicine and imaging
Link
https://link.springer.com/content/pdf/10.1007/s00066-023-02112-7.pdf
Reference8 articles.
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2. Couwenberg AM, Burbach JPM, Berbee M et al (2020) Efficacy of dose-escalated chemoradiation on complete tumor response in patients with locally advanced rectal cancer (RECTAL-BOOST): a phase 2 randomized controlled trial. Int J Radiat Oncol Biol Phys 108:1008–1018
3. Fokas E, Allgäuer M, Polat B et al (2019) Randomized phase II trial of chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: CAO/ARO/AIO-12. J Clin Oncol 37:3212–3222
4. Garcia-Aguilar J, Patil S, Gollub MJ et al (2022) Organ preservation in patients with rectal adenocarcinoma (OPRA) treated with total neoadjuvant therapy. J Clin Oncol 40:2546–2556
5. Gerard JP, Barbet N, Schiappa R et al (2023) Neoadjuvant chemoradiotherapy with radiation dose escalation with contact x‑ray brachytherapy boost or external beam radiotherapy boost for organ preservation in early cT2–cT3 rectal adenocarcinoma (OPERA): a phase 3, randomised controlled trial. Lancet Gastroenterol Hepatol 8:356–367
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