Pembrolizumab plus Radiochemotherapie bei lokal fortgeschrittenem Zervixkarzinom – die prospektive, randomisierte KEYNOTE-A18-Phase-3-Studie-Reference-Cited by-同舟云学术

Pembrolizumab plus Radiochemotherapie bei lokal fortgeschrittenem Zervixkarzinom – die prospektive, randomisierte KEYNOTE-A18-Phase-3-Studie

Published:2024-09-04 Issue: Volume: Page:
ISSN:0179-7158
Container-title:Strahlentherapie und Onkologie
language:de
Short-container-title:Strahlenther Onkol

Author:

Trommer Maike,Gaasch Aurélie,Corradini Stefanie

Funder

Universitätsklinikum Köln

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s00066-024-02298-4.pdf

Reference5 articles.

1. ENGOT-cx11/GOG-3047/KEYNOTE-A18 investigators, Lorusso D, Xiang Y, Hasegawa K et al (2024) Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial. Lancet 403(10434):1341–1350. https://doi.org/10.1016/S0140-6736(24)00317-9

2. Zentrum für Krebsregisterdaten, RKI Krebs in Deutschland 2019/2020. https://www.krebsdaten.de/Krebs/DE/Content/Publikationen/Krebs_in_Deutschland/kid_2023/kid_2023_c53_gebaermutterhals.pdf?__blob=publicationFile. Zugegriffen: 06.2024

3. Mileshkin LR, Moore KN, Barnes EH et al (2023) Adjuvant chemotherapy following chemoradiotherapy as primary treatment for locally advanced cervical cancer versus chemoradiotherapy alone (Outback): an international, open-label, randomised, phase 3 trial. Lancet Oncol 24(5):468–482. https://doi.org/10.1016/S1470-2045(23)00147-X

4. Monk BJ, Toita T, Wu X et al (2023) Durvalumab versus placebo with chemoradiotherapy for locally advanced cervical cancer (CALLA): a randomised, double-blind, phase 3 trial. Lancet Oncol 24(12):1334–1348. https://doi.org/10.1016/S1470-2045(23)00479-5

5. McCormack M, Gallardo Rincon D, Eminowicz G et al (2023) A randomised phase III trial of induction chemotherapy followed by chemoradiation compared with chemoradiation alone in locally advanced cervical cancer: the GCIG interlace trial. Ann Oncol 34:1276. https://doi.org/10.1016/j.annonc.2023.10.028