Osthole inhibits GSK-3β/AMPK/mTOR pathway-controlled glycolysis and increases radiosensitivity of subcutaneous transplanted hepatocellular carcinoma in nude mice
Author:
Funder
Research Fund of Nanjing Medical University
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Radiology, Nuclear Medicine and imaging
Link
https://link.springer.com/content/pdf/10.1007/s00066-023-02173-8.pdf
Reference35 articles.
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3. Zhang N, Liu XJ, Liu L, Deng ZS, Zeng QX, Pang WQ, Liu Y, Song DQ, Deng HB (2018) Glycogen synthase kinase-3beta inhibition promotes lysosome-dependent degradation of c‑FLIPL in hepatocellular carcinoma. Cell Death Dis 9:230
4. Fang GX, Zhang PL, Liu JF, Zhang X, Zhu XJ, Li R, Wang HY (2019) Inhibition of GSK-3β activity suppresses HCC malignant phenotype by inhibiting glycolysis via activating AMPK/mTOR signaling. Cancer Lett 463:11–26
5. Tang L, Wei F, Wu YF, He Y, Shi L, Xiong F, Gong ZJ, Guo C, Li XY, Deng H, Cao K, Zhou M, Xiang B, Li XL, Li Y, Li GY, Xiong W, Zeng ZY (2018) Role of metabolism in cancer cell radioresistance and radiosensitization methods. J Exp Clin Cancer Res 37:87
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