Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2-Reference-Cited by-同舟云学术

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Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2

Published:2015-07-14 Issue:10 Volume:51 Page:1056-1063
ISSN:1071-2690
Container-title:In Vitro Cellular & Developmental Biology - Animal
language:en
Short-container-title:In Vitro Cell.Dev.Biol.-Animal

Author:

Kus Gokhan,Kabadere Selda,Uyar Ruhi,Kutlu Hatice Mehtap

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Developmental Biology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s11626-015-9932-9.pdf

Reference24 articles.

1. Beckham TH, Elojeimy S, Cheng JC, Turner LS, Hoffman SR, Norris JS, Liu X (2010) Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials. Expert Opin Ther Targets 14:529–39

2. Draper JM, Xia Z, Smith RA, Zhuang Y, Wang W, Smith CD (2011) Discovery and evaluation of inhibitors of human ceramidase. Mol Cancer Ther 10:2052–61

3. Engedal N, Saatcioglu F (2001) Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features. Prostate 46:289–297

4. Gewies A, Rokhlin OW, Cohen MB (2000) Ceramide induces cell death in the human prostatic carcinoma cell lines PC3 and DU145 but does not seem to be involved in Fas-mediated apoptosis. Lab Invest 80:671–676

5. Holman DH, Turner LS, El-Zawahry A, Elojeimy S, Liu X, Bielawski J, Szulc ZM, Norris K, Zeidan YH, Hannun YA, Bielwska A, Norris JS (2008) Lysosomotric acid ceramidase inhibitor induces apoptosis in prostate cancer cells. Cancer Chemother Paharmacol 61:231–242

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