Scalable and Robust Dual-Primal Newton–Krylov Deluxe Solvers for Cardiac Electrophysiology with Biophysical Ionic Models

Author:

Huynh Ngoc Mai Monica,Pavarino Luca F.ORCID,Scacchi Simone

Abstract

AbstractThe focus of this work is to provide an extensive numerical study of the parallel efficiency and robustness of a staggered dual-primal Newton–Krylov deluxe solver for implicit time discretizations of the Bidomain model. This model describes the propagation of the electrical impulse in the cardiac tissue, by means of a system of parabolic reaction-diffusion partial differential equations. This system is coupled to a system of ordinary differential equations, modeling the ionic currents dynamics. A staggered approach is employed for the solution of a fully implicit time discretization of the problem, where the two systems are solved successively. The arising nonlinear algebraic system is solved with a Newton–Krylov approach, preconditioned by a dual-primal Domain Decomposition algorithm in order to improve convergence. The theoretical analysis and numerical validation of this strategy has been carried out in Huynh et al. (SIAM J. Sci. Comput. 44, B224–B249, 2022) considering only simple ionic models. This paper extends this study to include more complex biophysical ionic models, as well as the presence of ischemic regions, described mathematically by heterogeneous diffusion coefficients with possible discontinuities between subregions. The results of several numerical experiments show robustness and scalability of the proposed parallel solver.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Istituto Nazionale di Alta Matematica ”Francesco Severi”

Horizon 2020 Framework Programme

Publisher

Springer Science and Business Media LLC

Subject

General Mathematics

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