Combination Antifungal Therapy: When, Where, and Why
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Microbiology (medical)
Link
http://link.springer.com/content/pdf/10.1007/s40588-015-0017-z.pdf
Reference53 articles.
1. Johnson MD, Perfect JR. Use of antifungal combination therapy: agents, order, and timing. Curr Fungal Infect Rep. 2010;4(2):87–95.
2. Lewis RE, Kontoyiannis DP. Rationale for combination antifungal therapy. Pharmacotherapy. 2001;21(8 Pt 2):149S–64.
3. Garbati MA, Alasmari FA, Al-Tannir MA, Tleyjeh IM. The role of combination antifungal therapy in the treatment of invasive aspergillosis: a systematic review. Int J Infect Dis: Int J Infect Dis. 2012;16(2):e76–81.
4. Ullmann AJ, Akova M, Herbrecht R, Viscoli C, Arendrup MC, Arikan-Akdagli S, et al. ESCMID guideline for the diagnosis and management of Candida diseases 2012: adults with haematological malignancies and after haematopoietic stem cell transplantation (HCT). Clin Microbiol Infect. 2012;18 Suppl 7:53–67.
5. Marr KA, Schlamm HT, Herbrecht R, Rottinghaus ST, Bow EJ, Cornely OA, et al. Combination antifungal therapy for invasive aspergillosis: a randomized trial. Ann Int Med. 2015;162(2):81–9. First major randomized controlled study to compare combination antifungal therapy to monotherapy using voriconazole with anidulafungin versus voriconazole alone. They used a homogeneous population and showed that overall no difference in mortality. However on a subset analysis suggests that patients with a positive galactomannan result may benefit from combination antifungal therapy.
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