Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity

Author:

Braslawsky Gary R.,Kadow Kathleen,Knipe Jay,McGoff Kerry,Edson Mary,Kaneko Takushi,Greenfield Robert S.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Immunology,Immunology and Allergy

Reference33 articles.

1. Braslawsky, GR, Greenfield RS (1989) Preclinical studies of adriamycin-antibody conjugates linked through the 13-keto position In: Rubinstein E, Adam D (eds) Recent advances in chemotherapy E. Lewis-Epstein Ltd., Tel-Aviv, Israel

2. Braslawsky GR, Yaakubowicz M, Frensdorff A, Witz IP (1976) Receptors for immune-complexes on cells within a non-lymphoid murine tumor, J Immunol 116: 1571–1578

3. Braslawsky GR, Ran M, Witz IP (1976) Tumor bound immunoglobulins: the relationship between the in vivo coating of tumor cells by potentially cytotoxic antitumor antibodies, and the expression of complex receptors in vivo. Int J Cancer 18: 116–121

4. Braslawsky GR, Serban D, Witz IP (1976) Receptors for immunecomplexes on non-lymphoic polyoma virus induced murine tumor cells. Eur J Immunol 6: 579–583

5. Braslawsky GR, Pearce W, Edson M, Greenfield RS (1990) Antitumor activity of Adriamycin immunoconjugates against human lymphoma xenograft in nude mice, Cancer Res 50: 6608–6614

Cited by 76 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. LC/MS Methods for Studying Lysosomal ADC Catabolism;Methods in Molecular Biology;2019-10-24

2. Transferrin Receptor and Targeting Strategies;Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis;2019

3. Activating Autophagy Enhanced the Antitumor Effect of Antibody Drug Conjugates Rituximab-Monomethyl Auristatin E;Frontiers in Immunology;2018-08-03

4. A new construct of antibody-drug conjugates for treatment of B-cell non-Hodgkin's lymphomas;European Journal of Pharmaceutical Sciences;2017-05

5. Technologies for Antibody-Drug Conjugation;Biosimilars of Monoclonal Antibodies;2016-12-01

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3