Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials
Author:
Publisher
Springer Science and Business Media LLC
Subject
Clinical Neurology
Link
http://link.springer.com/content/pdf/10.1007/s11940-019-0577-y.pdf
Reference91 articles.
1. Harris W. A case of pontine glioma, with special reference to the paths of gustatory sensation. Proc R Soc Med. 1926;19(Neurol Sect):1–5.
2. Louis DN, Perry A, Reifenberger G, et al. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol. 2016;131(6):803–20.
3. •• Khuong-Quang DA, Buczkowicz P, Rakopoulos P, et al. K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathol. 2012;124(3):439–47.
4. •• Wu G, Broniscer A, McEachron TA, et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet. 2012;44(3):251–3.
5. •• Schwartzentruber J, Korshunov A, Liu XY, et al. Driver mutations in histone H3.3 and chromatin remodeling genes in pediatric glioblastoma. Nature. 2012;482(7384):226–31.Wu et al., Khuong-Quang et al. and Schwartzentruber et al. discovered the highly recurrent H3 K27M mutation in DIPG and other pediatric midline gliomas. This discovery of an “oncohistone” has revolutionized our understanding of the pathophysiology of this disease and underscores the central role for epigenetic dysregulation in DIPG and other pediatric malignancies.
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