Statins in Ischemic Stroke Prevention: What Have We Learned in the Post-SPARCL (The Stroke Prevention by Aggressive Reduction in Cholesterol Levels) Decade?-Reference-Cited by-同舟云学术

Statins in Ischemic Stroke Prevention: What Have We Learned in the Post-SPARCL (The Stroke Prevention by Aggressive Reduction in Cholesterol Levels) Decade?

Published:2019-04-08 Issue:5 Volume:21 Page:
ISSN:1092-8480
Container-title:Current Treatment Options in Neurology
language:en
Short-container-title:Curr Treat Options Neurol

Author:

Castilla-Guerra Luis,Fernandez-Moreno María del Carmen,Leon-Jimenez David,Rico-Corral Miguel Angel

Publisher

Springer Science and Business Media LLC

Subject

Neurology (clinical)

Link

http://link.springer.com/content/pdf/10.1007/s11940-019-0563-4.pdf

Reference40 articles.

1. Castilla-Guerra L, Fernandez-Moreno M, Colmenero-Camacho MA. Statins in stroke prevention: present and future. Curr Pharm Des. 2016;22:4638–44.

2. Amarenco P, Labreuche J. Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention. Lancet Neurol. 2009;8:453–63.

3. Wang W, Zhang B. Statins for the prevention of stroke: a meta-analysis of randomized controlled trials. PLoS One. 2014;9(3):e92388.

4. Wang J, Chen D, Li DB, et al. Comparison of the efficacy and safety of intensive-dose and standard-dose statin treatment for stroke prevention. A meta-analysis. Medicine (Baltimore). 2016;95(39):e4950.

5. •• The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med. 2006;355:549–59 Landmark study in vascular neurology. It was specifically designed to investigate the effect of the reduction of cholesterol levels with a statin in secondary stroke prevention, and was the first trial to show the benefits of statin therapy in preventing recurrent stroke.

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