Omega-3 fatty acid protects cardiomyocytes against hypoxia-induced injury through targeting MiR-210-3p/CASP8AP2 axis

Author:

Yu Xueju,Liu Fengyao,Liu Yuting,Bai Bingqing,Yin Han,Wang Haochen,Feng Yingqing,Ma Huan,Geng QingshanORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Medical Science and Technology Foundation of Guangdong Province

Traditional Chinese Medicine Bureau of Guangdong Province

High-level Hospital Construction Project of Guangdong Provincial People’s Hospital

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,General Medicine

Reference28 articles.

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2. Olivetti G, Quaini F, Sala R, Lagrasta C, Corradi D, Bonacina E, Gambert SR, Cigola E, Anversa P (1996) Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. J Mol Cell Cardiol 28:2005–2016. https://doi.org/10.1006/jmcc.1996.0193

3. Palojoki E, Saraste A, Eriksson A, Pulkki K, Kallajoki M, Voipio-Pulkki LM, Tikkanen I (2001) Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats. Am J Physiol Heart Circ Physiol 280:H2726–H2731. https://doi.org/10.1152/ajpheart.2001.280.6.H2726

4. Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA (2017) Hypoxia induces heart regeneration in adult mice. Nature 541:222–227. https://doi.org/10.1038/nature20173

5. Alexander DD, Miller PE, Van Elswyk ME, Kuratko CN, Bylsma LC (2017) A meta-analysis of randomized controlled trials and prospective cohort studies of eicosapentaenoic and docosahexaenoic long-chain omega-3 fatty acids and coronary heart disease risk. Mayo Clinic Proc 92:15–29. https://doi.org/10.1016/j.mayocp.2016.10.018

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