Variability in Human In Vitro Enzyme Kinetics-Reference-Cited by-同舟云学术

Variability in Human In Vitro Enzyme Kinetics

Published:2021 Issue: Volume: Page:443-479
ISSN:1064-3745
Container-title:Methods in Molecular Biology
language:
Short-container-title:

Author:

Gibson Christopher R.,Wang Ying-Hong,Varkhede Ninad,Ma Bennett

Publisher

Springer US

Link

https://link.springer.com/content/pdf/10.1007/978-1-0716-1554-6_16

Reference157 articles.

1. Shimada T, Yamazaki H, Mimura M et al (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270(1):414–423

2. Gomez-Lechon MJ, Castell JV, Donato MT (2007) Hepatocytes—the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo. Chem Biol Interact 168(1):30–50

3. Rowland-Yeo K (2004) Abundance of cytochromes P450 in human liver: a meta-analysis. Br J Clin Pharmacol 57:687

4. Hallifax D, Houston J (2009) Methodological uncertainty in quantitative prediction of human hepatic clearance from in vitro experimental systems. Curr Drug Metab 10(3):307–321

5. Gomez-Lechon M, Donato M, Castell J et al (2004) Human hepatocytes in primary culture: the choice to investigate drug metabolism in man. Curr Drug Metab 5(5):443–462

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Atypical kinetics of cytochrome P450 enzymes in pharmacology and toxicology;Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary;2022

2. Reaction Phenotyping of Low-Turnover Compounds in Long-Term Hepatocyte Cultures Through Persistent Selective Inhibition of Cytochromes P450;Drug Metabolism and Disposition;2021-08-18