Localization of Mitochondrial Nucleoids by Transmission Electron Microscopy Using the Transgenic Expression of the Mitochondrial Helicase Twinkle and APEX2
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Publisher
Springer US
Link
https://link.springer.com/content/pdf/10.1007/978-1-0716-2922-2_13
Reference22 articles.
1. Stewart JB, Chinnery PF (2020) Extreme heterogeneity of human mitochondrial DNA from organelles to populations. Nat Rev Genet 22:106. https://doi.org/10.1038/s41576-020-00284-x
2. Kukat C, Wurm CA, Spahr H, Falkenberg M, Larsson NG, Jakobs S (2011) Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA. Proc Natl Acad Sci U S A 108(33):13534–13539. https://doi.org/10.1073/pnas.1109263108
3. Peter B, Falkenberg M (2020) TWINKLE and other human mitochondrial DNA helicases: structure, function and disease. Genes (Basel) 11(4):doi:10.3390/genes11040408
4. Tyynismaa H, Sembongi H, Bokori-Brown M, Granycome C, Ashley N, Poulton J, Jalanko A, Spelbrink JN, Holt IJ, Suomalainen A (2004) Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number. Hum Mol Genet 13(24):3219–3227. https://doi.org/10.1093/hmg/ddh342
5. Nass MMK, Nass S (1963) Intramitochondrial fibers with DNA characteristics. 1. Fixation and electron staining reactions. J Cell Biol 19(3):593-&. https://doi.org/10.1083/jcb.19.3.593
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