Unilateral Lung Removal in Combination with Monocrotaline or SU5416 in Rodents: A Reliable Model to Mimic the Pathology of the Human Pulmonary Hypertension

Author:

Katz Michael G.ORCID,Hadas Yoav,Shtraizent Nataly,Ravvin Shana,Madjarov Jeko M.,Eliyahu Efrat

Publisher

Springer US

Reference21 articles.

1. Stenmark KR, Meyrick B, Galie N et al (2009) Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. Am J Phys Lung Cell Mol Phys 297:L1013–L1032

2. Gomez-Arroyo JG, Farkas L, Alhussaini AA et al (2012) The monocrotaline model of pulmonary hypertension in perspective. Am J Phys Lung Cell Mol Phys 302:L363–L369

3. Tuder RM, Marecki JC, Richter A et al (2007) Pathology of pulmonary hypertension. Clin Chest Med 28:23–42

4. Stenmark KR, Fagan KA, Frid MG (2006) Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res 99:675–691

5. Dempsey EC, Wick MJ, Karoor V et al (2009) Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. Am J Pathol 174:782–796

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