A Method for Perfusion of Tissue-Isolated Human Tumor Xenografts in Nude Rats to Investigate the Oncostatic Role of the Physiological Nocturnal Melatonin Signal

Author:

Dauchy Robert T.,Hill Steven M.,Blask David E.

Publisher

Springer US

Reference28 articles.

1. Sauer LA, Stayman JW III, Dauchy RT (1982) Amino acid, glucose and lactic acid utilization in vivo by rat tumors. Cancer Res 42:4090–4097

2. Dauchy RT, Sauer LA (1986) Preparation of “tissue-isolated” rat tumors for perfusion: a new surgical technique that preserves continuous blood flow. Lab Anim Sci 36:678–681

3. Blask DE, Dauchy RT, Sauer LA et al (2003) Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. Breast Cancer Res Treat 79:313–320

4. Blask DE, Brainard GC, Dauchy RT et al (2005) Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats. Cancer Res 65:11174–11184

5. Dauchy EM, Dauchy RT, Sauer LA et al (2006) Human breast cancer xenografts perfused in situ in rats with growth-inhibitory agents: a new perfusion system that minimizes delivery time. J Am Assoc Lab Anim Sci 45:38–44

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