1. Crum-Brown A, Fraser TR (1865) The connection of chemical constitution and physiological action. Trans R Soc Edinb 25(1968–1969):257
2. Crum-Brown A, Fraser TR (1868) On the connection between chemical constitution and physiological action; with special reference to the physiological action of the salts of the ammonium bases derived from strychnia, brucia, thebaia, codeia, morphia, and nicotia. J Anat Physiol 2(2):224–242
3. Hansch C (1969) A quantitative approach to biochemical structure-activity relationships. Acc Chem Res 2:232–239
4. Devinyak OT, Lesyk RB (2016) 5-year trends in QSAR and its machine learning methods. Curr Comput Aided Drug Des 12(4):265–271
5. Mitchell TM (1997) Machine learning, vol 45. McGraw Hill, Ridge, pp 870–877