Identifying CAR Modulators Utilizing a Reporter Gene Assay
Author:
Publisher
Springer US
Link
https://link.springer.com/content/pdf/10.1007/978-1-0716-2213-1_4
Reference23 articles.
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2. Wang H, LeCluyse E (2003) Role of orphan nuclear receptors in the regulation of drug-Metabolising enzymes. Clin Pharmacokinet 42(15):1331–1357. https://doi.org/10.2165/00003088-200342150-00003
3. Lynch C, Pan Y, Li L, Heyward S, Moeller T, Swaan PW, Wang H (2014) Activation of the constitutive androstane receptor inhibits gluconeogenesis without affecting lipogenesis or fatty acid synthesis in human hepatocytes. Toxicol Appl Pharmacol 279(1):33–42. https://doi.org/10.1016/j.taap.2014.05.009
4. Dong B, Saha PK, Huang W, Chen W, Abu-Elheiga LA, Wakil SJ, Stevens RD, Ilkayeva O, Newgard CB, Chan L, Moore DD (2009) Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease. Proc Natl Acad Sci U S A 106:18831–18836. https://doi.org/10.1073/pnas.0909731106
5. De Mattia E, Cecchin E, Roncato R, Toffoli G (2016) Pregnane X receptor, constitutive androstane receptor and hepatocyte nuclear factors as emerging players in cancer precision medicine. Pharmacogenomics 17(14):1547–1571. https://doi.org/10.2217/pgs-2016-0095
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