ICI 141,292 (epanolol) —pharmacokinetics after single and repeated oral administration in the elderly with moderate renal impairment

Author:

Laher M. S.,Crome R,Rakhra G. S.,Ankier S. I.,Cockshott I. D.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference11 articles.

1. Bilski AJ, Hatton R, Moors J, Nuttall A, Shaw G (1988) The chro- notropic properties of epanolol in the anaesthetised dog. Br J Pharmaco1 94:426 P

2. Cockshott ID (1989) The pharmacokinetics of ICI 141,292 in healthy young volunteers and comparative data in elderly patients with angina and subjects with renal or hepatic impairment. Drugs [Suppl 2] 38:10–17

3. Harry JD, NorrisSC, Young J, Wardleworth A, Corlett C, Morton P (1984) The demonstration of ICI 141,292 as a beta-adreno- ceptor blocking agent in man. Br J Clin Pharmaco1 18:291P

4. Hedberg A, Mattsson H, Lundgren B, Carlsson E (1982) Beta adrenoceptor dynamics of prenalterol and isoproterenol. Fed Proc 41:1054

5. Jack DB, Quarterman CR Zaman R, Kendall MJ (1982) Variability of beta-blocker pharmacokinetics in young volunteers. Eur J Clin Pharmaco1 23:37–42

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