Metabolism and hepatotoxicity of N,N-dimethylformamide, N-hydroxymethyl-N-methylformamide, and N-methylformamide in the rat-Reference-Cited by-同舟云学术

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Metabolism and hepatotoxicity of N,N-dimethylformamide, N-hydroxymethyl-N-methylformamide, and N-methylformamide in the rat

Published:1994-05 Issue:5 Volume:68 Page:291-295
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Van den Bulcke M.,Rosseel M. T.,Wijnants P.,Buylaert W.,Belpaire F. M.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s002040050071.pdf

Reference19 articles.

1. Brindley C, Gesher A, Ross D (1983) Studies of the metabolism of dimethylformamide in mice. Chem Biol Interact 45: 387–392

2. Cross H, Dayal R, Hyland R, Gesher A (1990)N-Alkylformamides are metabolized toN-alkylcarbamoylating species by hepatic microsomes from rodents and humans. Chem Res Toxicol 3: 357–362

3. Gerlach U (1957) Pathologischer Ubertritt von Sorbitdehydrogenase ins Blut bei Lebererkrankungen. Klin Wochenschr. 35: 1144–1145

4. Gesher A (1993) Metabolism ofN, N-dimethylformamide: key to the understanding of its toxicity. Chem Res Toxicol 6: 245–251

5. Gesher A, Gibson NW, Hickman JW, Langdon SP, Ross D, Atassi A (1982)N-Methylformamide: antitumor activity and metabolism in mice. Br J Cancer 45: 843–950

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