T-Cell Epitopes in Type 1 Diabetes Autoantigen Tyrosine Phosphatase IA-2: Potential for Mimicry with Rotavirus and Other Environmental Agents

Author:

Honeyman Margo C.,Stone Natalie L.,Harrison Leonard C.

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine

Reference39 articles.

1. Rabin DU, Pleasic SM, Shapiro JA, et al. (1994) Islet cell antigen 512 is a diabetes-specific islet autoantigen related to tyrosine phosphatases. J. Immunol. 152: 3183–3188.

2. Lan MS, Lu J, Goto Y, Notkins AL. (1994) Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma. DNA Cell Biol. 13: 505–514.

3. Solimena M, Dirkx R, Hermel JM, et al. (1996) ICA512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granules. EMBO J. 15: 2102–2114.

4. Bonifacio E, Lampasona V, Genovese S, Ferrari M, Bosi E. (1995) Identification of protein tyrosine phosphatase-like IA-2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies. J. Immunol. 155: 5419–5426.

5. Cui L, Wei-Ping Y, deAizpurua HJ, Schmidli RS, Pallen CJ. (1996) Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (FTP), a novel receptor-like FTP and autoantigen in insulin-dependent diabetes. J. Biol. Chem. 271: 24817–24823.

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