Preclinical and clinical development of palbociclib and future perspectives

Author:

de Dueñas E. MartínezORCID,Gavila-Gregori J.,Olmos-Antón S.,Santaballa-Bertrán A.,Lluch-Hernández A.,Espinal-Domínguez E. J.,Rivero-Silva M.,Llombart-Cussac A.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference31 articles.

1. Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer. 2009;9:153–66.

2. (FDA) USFDAUS. Palbociclib (IBRANCE). 2017. https://www.fda.gov/Drugs/InformationOnDrugs/ApprovedDrugs/ucm549978.htm . Accessed 30 June 2017.

3. (EMA) EMA. Ibrance (palbociclib). 2017. http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/003853/human_med_002034.jsp&mid=WC0b01ac058001d124 . Accessed 30 June 2017.

4. Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature. 2012;490:61–70.

5. Witkiewicz AK, Knudsen ES. Retinoblastoma tumor suppressor pathway in breast cancer: prognosis, precision medicine, and therapeutic interventions. Breast Cancer Res. 2014;16:207.

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