1. Humblet C, Marshall GR. Pharmacophore identification and receptor mapping. Annu Rep Med Chem. 1980;15:267–76.
2. Ariens E. Drug Design. Vol 1. Academic Press, London, 1971.
3. Sneader W. Drug Discovery. A history. J Wiley, Chichester, 2005.
4. Monge A. Personal communication.
5. The most paradigmatic example in medicinal chemistry is penicillin. The availability of 6-APA by fermentation opened the new world of antibiotic β-lactamics.